DICL_CP_0329121 - DICL Database

Basic Molecular Information

Basic Information

DICL ID

DICL_CP_0329121

PubChem CID

444899

Molecular Formula

C₂₀H₃₂O₂

Molecular Weight

304.474 g/mol

Synonyms/Alias

[arachidonic acid; 506-32-1; arachidonate; (5Z;8Z;11Z;14Z)-icosa-5;8;11;14-tetraenoic acid; Immunocytophyte; (all-Z)-5;8;11;14-Eicosatetraenoic acid; cis-5;8;11;14-Eicosatetraenoic acid; 5;8;11;14-Eic...[arachidonic acid; 506-32-1; arachidonate; (5Z;8Z;11Z;14Z)-icosa-5;8;11;14-tetraenoic acid; Immunocytophyte; (all-Z)-5;8;11;14-Eicosatetraenoic acid; cis-5;8;11;14-Eicosatetraenoic acid; 5;8;11;14-Eicosatetraenoic acid; (all-Z)-; all-cis-5;8;11;14-eicosatetraenoic acid; Arachidonsaeure; 5Z;8Z;11Z;14Z-eicosatetraenoic acid; (5Z;8Z;11Z;14Z)-5;8;11;14-Eicosatetraenoic Acid; UNII-27YG812J1I; CCRIS 6312; CHEBI:15843; 27YG812J1I; EINECS 208-033-4; CHEMBL15594; AI3-09613; DTXSID4040420; Icosa-5;8;11;14-tetraenoic acid; MFCD00004417; (5Z;8Z;11Z;14Z)-5;8;11;14-Eikosatetraensaeure; 5Z;8Z;11Z;14Z-icosatetraenoic acid; FA 20:4; ARACHIDONIC ACID (20:4; n-6); (5Z;8Z;11Z;14Z)-Icosatetraenoic acid; 5;8;11;14-Eicosatetraenoic acid; C20:4; cis-Delta(5;8;11;14)-eicosatetraenoic acid; [1-14C]Arachidonic acid; 93444-49-6; (5Z;8Z;11Z;14Z)-5;8;11;14-Icosatetraenoic acid; ARACHIDONIC ACID (MART.); ARACHIDONIC ACID [MART.]; (14C)Arachidonic acid; Arachidonic Acid; 99%; Arachidonic Acid; >97%; Arachidonic Acid-d8 (Major; 10mg/ml in Methyl Acetate); 5;8;11;14-Icosatetraenoic Acid; arachidonic-acid; 1adl; 1gnj; 1vyg; (5Z;8Z;11Z;14Z)-5;8;11;14-Eicosatetraenoic-5;6;8;9;11;12;14;15-d8 Acid; (all-Z)-5;8;11;14-Eicosatetraenoic-5;6;8;9;11;12;14;15-d8 Acid; Arachidonic Acid-5;6;8;9;11;12;14;15-2H8;; cis;cis;cis;cis-5;8;11;14-Eicosatetraenoic acid; (14C)-arachidonic acid; Spectrum5_001910; Fatty Acid 20:4 n-6; SCHEMBL16162; BSPBio_001539; MLS001361328; ARACHIDONIC ACID [MI]; AA-[d8]; BML3-B03; GTPL2391; 5;8;11;14-Eicosatetraenoate; DTXCID2020420; BDBM22319; ARACHIDONIC ACID [WHO-DD]; CHEBI:137828; HMS1361M21; HMS1791M21; HMS1989M21; HMS3402M21; HMS3649B05; 5Z;8Z;11Z;14Z-Eicosatetraenoate; Arachidonic acid; >95.0% (GC); 5;8;11;14-Eicosatetraenoic acid; labeled with carbon-14; (all-Z)-; Arachidonic acid; analytical standard; cis-D5;8;11;14-Eicosatetraenoate; LMFA01030001; s6185; AKOS015950830; CCG-214838; DB04557; FS-5880; 5;8;11;14-all-cis-Eicosatetraenoate; all-cis-5;8;11;14-Eicosatetraenoate; ARACHIDONIC ACID (20:4 n-6); IDI1_034009; cis-D5;8;11;14-Eicosatetraenoic acid; NCGC00094608-01; NCGC00094608-02; NCGC00094608-03; NCGC00094608-04; NCGC00094608-05; NCGC00094608-06; (all-Z)-5;8;11;14-Eicosatetraenoate; AC-14348; AC-33769; BP-29803; Eicosa-5Z;8Z;11Z;14Z-tetraenoic acid; SMR000857374; 5;8;11;14-all-cis-Eicosatetraenoic acid; All-cis-icosa-5;8;11;14-tetraenoic acid; HY-109590; A0781; all-cis-eicosa-5;8;11;14-tetraenoic acid; CS-0032762; >95.0% (GC); 5-cis;8-cis;11-cis;14-cis-Eicosatetraenoate; C00219; W15452; FA(20:4(5Z;8Z;11Z;14Z)); 5-cis;8-cis;11-cis;14-cis-Eicosatetraenoic acid; A929392; Q407699; SR-01000838311; SR-01000838311-2; BRD-K03070961-001-02-8; BRD-K03070961-001-04-4; (5Z;8Z;11Z;14Z)-icosa-5;8;11;14-tetraenoicacid; (5Z;8Z;11Z;14Z)-5;8;11;14-Icosatetraenoic acid #; Arachidonic acid; from non-animal source; >=98.5% (GC); Arachidonic acid; from porcine liver; >=99% (GC); liquid; D18DBC10-379C-4E78-9A50-8B791A2F4E68; Arachidonic acid; from porcine liver; >=85% (capillary GC); liquid; Arachidonic acid; 1.0 mg/mL in ethanol; certified reference material; Arachidonic acid; from porcine liver; BioReagent; suitable for cell culture; >=99% (GC); Immunocytophyte ; arachidonate ; Immunocytophyt ; Vevodar]

InChI Key

YZXBAPSDXZZRGB-DOFZRALJSA-N

InChI

InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2...

IUPAC Name

(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid

CAS Number

506-32-1

Structure Information

Chemical Structure Visualization

SMILES Notation

2D Molecular Drawing

Carbon (C)

Hydrogen (H)

Oxygen (O)

Nitrogen (N)

Sulfur (S)

SDF

54 53 0 0 0 0 0 0 0 0999 V2000
-7.3684 1.1896 0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0
-7.5368 -0.3275 -0.0664 C 0 0 0 0 0 0 0 0 0 0 0 0
-6.7375 -0.960...

Download SDF File (4546 bytes)

Experimental Data

Activity Data

Target Ion Channel

Piezo1

Uniprot Accession Number

Q92508

Function

Inactive

Species

Homo sapiens (Human)

IC₅₀

N/A (Not available)

EC₅₀

N/A (Not available)

K_i

N/A (Not available)

K_d

N/A (Not available)

Inhibition

No effect

Experimental Conditions

pH 7.3

Holding Potential

Not specified

Temperature

Room Temperature

Test Method

Fluorometric Imaging Plate Reader (FLIPR) Membrane Potential Assay (Calcium imaging)

Test Species

HEK293 cell (Homo sapiens embryonic kidney 293 cell)

Binding Information

Binding Site

Not specified

Binding Site Residue

Not specified

Disease Information

Related Disease

Not specified

References

DOI

10.1038/s41467-019-09055-7

URL

N/A (Not available)

PMID

30867417

Patent

N/A (Not available)

Computed Properties

Heavy Atom Count

Rotatable Bonds

logP

6.2167

Complexity

96.0398

TPSA (Å²)

37.3

H-Bond Donors

H-Bond Acceptors

Ring Count

New Search

Molecular Details

Basic Molecular Information

Basic Information

Structure Information

Chemical Structure Visualization

Experimental Data

Activity Data

Experimental Conditions

Binding Information

Disease Information

References

Computed Properties